The one-off gig also includes improvisational jazz drummer Steven Noble.
The newly minuted gang of four are offering fans a once-in-a-lifetime gig.
The concert take places in Greenville, South Carolina this November.
Travis Scott, Earl Sweatshirt, Miguel, John Mayer, and Vince Staples will also perform.
Chad Smith-led rock ‘n’ roll supergroup to play Will Ferrell’s “Best Night of Your Life” charity concert
The one-off performance promises Coldplay singer Chris Martin, Pearl Jam guitarist Mike McCready, Chili Peppers guitarist Josh Klinghoffer, and Guns N’ Roses bassist Duff McKagan.
Eddie Vedder joins Will Ferrell, Chad Smith, Mike McCready, and Brandi Carlile to cover Depeche Mode: Watch
The all-star live collaboration capped off the charity event “One Classy Night In Seattle.”
RiRi also delivered “Wild Thoughts” and her N.E.R.D. collaboration “Lemon”.
Proceeds from the event will go to natural disaster relief efforts.
100% of the profits from the show will go to the Charlottesville Area Community Foundation.
Cat Power and Talib Kweli are also expected to make their voices heard at the climate change event.
Lineup also features The Wallflowers’ Jakob Dylan, E Street Band keyboardist Roy Bittan, and Goldfrapp’s Davide Rossi.
The 25-song set featured appearances from Paul Stanley, Perry Farrell, Sammy Hagar, Stewart Copeland, Steve Jones, and Jason Bonham.